Ischemic Stroke Induces Rapid Renal Oxidative Stress and Lipometabolic Change
نویسندگان
چکیده
Objective: Stroke is associated with high risks for mortality. The bidirectional communication between ischemic brain and other organ dysfunctions widely recognized. However, the mechanisms underlying cerebrorenal crosstalk remains unclear. Herein, we investigated effect of stroke on kidney using a middle cerebral artery occlusion (MCAO) model. Moreover, explored effects overexpression liver-type fatty acid binding protein (L-FABP), as antioxidant role in this disease.
منابع مشابه
Hyperhomocysteinemia and oxidative stress in ischemic stroke.
3. Liebeskind DS, Kidwell CS, Saver JL. Empiric evidence of publication bias affecting acute stroke clinical trials. Stroke. 1999;30:268. Abstract. 4. Bath FJ, Owen VE, Bath PM. Quality of full and final publications reporting acute stroke trials: a systematic review. Stroke. 1998;29: 2203–2210. Response Dr Saver and his colleagues were kind enough to provide me with their list of acute trials....
متن کاملHyperhomocysteinemia and Oxidative Stress in Ischemic Stroke
3. Liebeskind DS, Kidwell CS, Saver JL. Empiric evidence of publication bias affecting acute stroke clinical trials. Stroke. 1999;30:268. Abstract. 4. Bath FJ, Owen VE, Bath PM. Quality of full and final publications reporting acute stroke trials: a systematic review. Stroke. 1998;29: 2203–2210. Response Dr Saver and his colleagues were kind enough to provide me with their list of acute trials....
متن کاملThe Evaluation and Comparison of Oxidative Stress in Hemorrhagic and Ischemic Stroke
Background: Among different mechanisms, oxidative stress has a possible role in neural injury in cerebrovascular events. Objectives: Assessment the oxidants-antioxidants imbalance in ischemic and hemorrhagic strokes. Materials and Methods: Serum level of malondialdehyde, the main marker of lipid peroxidation, and total antioxidant capacity were measured in a group of 48 stroke patients consis...
متن کاملOxidative stress--assassin behind the ischemic stroke.
Ischemic stroke is the second leading cause of death and disability worldwide and is associated with significant clinical and socioeconomic implications, emphasizing the need for effective therapies. Several neuroprotective strategies have failed in clinical trials because of poor knowledge of the molecular processes flanked with ischemic stroke. Therefore, uncovering the molecular processes in...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 2021
ISSN: ['2188-2126', '2187-9737']
DOI: https://doi.org/10.14789/jmj.2021.67.jmj20-oa05